Pharmacology 6

     

 

 

 

Question # 1 (Multiple Choice) Least addiction/abuse liability:

A) hydromorphone
B) oxycodone
C) nalbuphine
D) codeine
E) methadone

Question # 2 (Multiple Answer) Choose (the) pure narcotic antagonist(s):

A) pentazocine
B) naloxone
C) naltrexone
D) codeine
E) nallorphine

Question # 3 (Multiple Answer) Possible mechanisms responsible for opioid-mediated flushing and warming of the skin:

A) alpha1 receptor activation
B) histamine release
C) central effects
D) adenosine receptor blockade
E) inhibition of nitric oxide synthase

Question # 4 (Multiple Answer) Reverses opioid-mediated truncal rigidity:

A) IV fentanyl
B) naltrexone
C) succinylcholine
D) nalmefene
E) oxycodone

Question # 5 (True/False) relatively long-lasting narcotic antagonist

A) naloxone
B) nalmefene

Question # 6 (Multiple Answer) Rationale for I.V. morphine to manage dyspnea secondary to acute pulmonary edema:

A) reduce perception of shortness of breath
B) decrease preload
C) decreased afterload
D) decrease heart rate
E) increase ventilation rate

Question # 7 (Multiple Answer) Prescribed to manage diarrhea

A) alfentanil
B) difenoxin
C) loperamide
D) diphenoxylate
E) hydromorphone

Question # 8 (Multiple Choice) Pain most effectively relieved by opioid agonists:

A) severe, constant pain
B) intermittent sharp pain

Question # 9 (Multiple Choice) Most current opioid analgesics act at this opioid receptor subtype:

A) sigma
B) kappa
C) delta
D) epsilon
E) mu

Question # 10 (Multiple Answer) Pure narcotic antagonists:

A) nalbuphine
B) naltrexone
C) fentanyl
D) pentazocine
E) naloxone

 

Question # 1 (Multiple Choice) Least addiction/abuse liability:

Answer: (C) nalbuphine

Question # 2 (Multiple Answer) Choose (the) pure narcotic antagonist(s):

(B) naloxone

(C) naltrexone



Question # 3 (Multiple Answer) Possible mechanisms responsible for opioid-mediated flushing and warming of the skin:

(B) histamine release

(C) central effects



Question # 4 (Multiple Answer) Reverses opioid-mediated truncal rigidity:

(B) naltrexone

(C) succinylcholine

(D) nalmefene


Question # 5 (True/False) relatively long-lasting narcotic antagonist

Answer: False


Question # 6 (Multiple Answer) Rationale for I.V. morphine to manage dyspnea secondary to acute pulmonary edema:

(A) reduce perception of shortness of breath

(B) decrease preload

(C) decreased afterload


Qestion # 7 (Multiple Answer) Prescribed to manage diarrhea

(B) difenoxin

(C) loperamide

(D) diphenoxylate


Question # 8 (Multiple Choice) Pain most effectively relieved by opioid agonists:

Answer: (A) severe, constant pain


Question # 9 (Multiple Choice) Most current opioid analgesics act at this opioid receptor subtype:

Answer: (E) mu


Question # 10 (Multiple Answer) Pure narcotic antagonists:

(B) naltrexone

(E) naloxone

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Question # 1 (Multiple Answer) Excessive anticoagulant effect in bleeding due to warfarin can be reversed by:

A) stopping the drug
B) large doses of vitamin K
C) factor IX concentrates
D) cholestyramine
E) diuretics

Question # 2 (Multiple Answer) Protease inhibitor(s) that inactivators coagulation proteins escaping from sites of vessel injury:

A) alpha2-macroglobulin
B) alpha2-antiplasmin
C) antithrombin III
D) alpha1 antiprotease
E) streptokinase

Question # 3 (Multiple Choice) Cutaneous necrosis was reduced protein C activity occurs during the first weeks of therapy with:

A) streptokinase
B) abciximab
C) warfarin
D) ticlopidine
E) aspirin

Question # 4 (Multiple Answer) Coagulation Factor(s) targets of heparin:

A) fibrinogen
B) proaccelerin
C) prothrombin
D) Christmas factor
E) antihemophilic globulin (AHG)

Question # 5 (Multiple Choice) Thrombus type most likely to be formed in low pressure veins

A) white thrombus
B) red thrombus

Question # 6 (True/False) Warfarin crosses the placental barrier:

A) true
B) false

Question # 7 (Multiple Choice) Synonym for factor VII:

A) proaccelerin
B) prothrombin
C) proconvertin
D) Christmas factor
E) Fibrin-stabilizing factor

Question # 8 (Multiple Answer) Fibrolytic drugs:

A) streptokinase
B) alteplase
C) reteplase
D) urokinase
E) cyclooxygenase

Question # 9 (Multiple Choice) Immediate hemostatic responds to the damage vessel:

A) platelet adhesion
B) platelet aggregation
C) platelet viscous metamorphosis
D) vasospasm
E) white thrombus formation

Question # 10 (Multiple Answer) Coumarin anticoagulants resulted in biologically inactive forms of:

A) factor VII
B) factor IX
C) factor X
D) anticoagulant protein C
E) anticoagulant protein S

Question # 11 (Multiple Answer) Increases prothrombin time:

A) cimetadine
B) metronidazole
C) trimethoprim-sulfamethoxazole
D) fluconazole
E) disulfram

Question # 12 (Multiple Choice) Mouse/human chimeric monoclonal antibody -- blocks IIb/IIIb platelet receptor

A) ticlopidine
B) timolol
C) abciximab
D) eicosapentaenoic acid
E) streptokinase

 

Question # 1 (Multiple Answer) Excessive anticoagulant effect in bleeding due to warfarin can be reversed by:

(A) stopping the drug

(B) large doses of vitamin K

(C) factor IX concentrates


Question # 2 (Multiple Answer) Protease inhibitor(s) that inactivators coagulation proteins escaping from sites of vessel injury:

(A) alpha2-macroglobulin

(B) alpha2-antiplasmin

(C) antithrombin III

(D) alpha1 antiprotease



Question # 3 (Multiple Choice) Cutaneous necrosis was reduced protein C activity occurs during the first weeks of therapy with:

Answer: (C) warfarin


Question # 4 (Multiple Answer) Coagulation Factor(s) targets of heparin:

(C) prothrombin

(D) Christmas factor


Question # 5 (Multiple Choice) Thrombus type most likely to be formed in low pressure veins

Answer: (B) red thrombus

Question # 6 (True/False) Warfarin crosses the placental barrier:

Answer: True


Question # 7 (Multiple Choice) Synonym for factor VII:

Answer: (C) proconvertin


Question # 8 (Multiple Answer) Fibrolytic drugs:

(A) streptokinase

(B) alteplase

(C) reteplase

(D) urokinase


Question # 9 (Multiple Choice) Immediate hemostatic responds to the damage vessel:

Answer: (D) vasospasm


Question # 10 (Multiple Answer) Coumarin anticoagulants resulted in biologically inactive forms of:

(A) factor VII

(B) factor IX

(C) factor X

(D) anticoagulant protein C


Question # 11 (Multiple Answer) Increases prothrombin time:

(A) cimetadine

(B) metronidazole

(C) trimethoprim-sulfamethoxazole

(D) fluconazole

(E) disulfram


Question # 12 (Multiple Choice) Mouse/human chimeric monoclonal antibody -- blocks IIb/IIIb platelet receptor

Answer: (C) abciximab